PE-Labeled Human HLA-A*24:02&B2M&EBV EBNA3A (RYSIFFDYM) Tetramer Protein

DESCRIPTION

Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC). Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research. Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC). Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research. The Human HLA-A*2402 EBV EBNA3A (RYSIFFDYM) complex protein is a complex of HLA-A*2402 of the MHC Class I, B2M and RYSIFFDYM peptide of the EBV EBNA3A.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 25ug
Buffer: PBS, 1% BSA, pH7.4
Format: Powder
Source: PE-Labeled Human HLA-A*24:02&B2M&EBV EBNA3A (RYSIFFDYM) Tetramer Protein (HLA-HP2H8) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*24:02) & Ile 21 - Met 119 (B2M) & RYSIFFDYM peptide (Accession # AAA59600.1 (HLA-A*24:02) & P61769 (B2M) & RYSIFFDYM).
Storage: -20℃, aviod light
Category: Fluorescent labeled protein
Molecule: HLA-A*2402 & B2M & EBV EBNA3A (RYSIFFDYM)
Conjugate: PE Labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gly 25 - Thr 305 (HLA-A*24:02) & Ile 21 - Met 119 (B2M) & RYSIFFDYM peptide
Swiss-prot: AAA59600.1 | P61769 & RYSIFFDYM
Package Size: 25ug*1
Characteristics: PE-Labeled Human HLA-A*24:02&B2M&EBV EBNA3A (RYSIFFDYM) Tetramer Protein is assembled by biotinylated monomer (HLA-H82E4) and PE-labeled streptavidin. Biotinylated Human HLA-A*24:02&B2M&EBV EBNA3A (RYSIFFDYM) Complex Protein is produced by co-expression of HLA and B2M loaded with EBV EBNA3A peptide. Biotinylated Human HLA-A*24:02&B2M&EBV EBNA3A (RYSIFFDYM) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 35.8 kDa and 14.0 kDa
Shipping Condition: RT
Species Reactivity: Human
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