DESCRIPTION

• Shiptemp: -80°C (dry ice)
• Synonyms: PTPN1, Protein tyrosine phosphatase 1B, ptp
• Warnings: Avoid freeze/thaw cycles.
• Category: Protein Phosphatase/Assay Kit
• References: 1. Gee, K.R., et al., Anal Biochem, 1999 Aug 15; 273(1):41-8. 2. Brown-Shimer, S., et al., 1992 Jan 15; 52(2):478-82.
• Description: Protein phosphorylation is one of the most important post-translational modification processes. Phosphorylation is reversibly regulated by Protein Kinases (PKs) and Protein Phosphatases (PTPs). PTP1B (PTPN1) is known to catalyze dephosphorylation of insulin receptor kinases and plays a critical role in insulin signaling. The Fluorogenic PTP1B (Catalytic Region) Assay Kit is designed to inhibitors of the catalytic region of PTP1B in a homogeneous assay with no time-consuming washing steps. Note: To identify inhibitors of the regulatory region of PTP1B, please use our Fluorogenic PTP1B (Full Length) Assay Kit, #79766).
• Methodology: Fluorogenic
• Supplied As: he PTP1B assay kit comes in a convenient 96-well format, with purified PTP1B enzyme, fluorogenic substrate, and PTP assay buffer for 96 enzyme reactions.
• Unspsc Code: 41105331
• Unspsc Name: Protein chemifluorescent detection reagents or kits or substrates
• Applications: Great for studying enzyme kinetics and HTS applications.
• Product Type: Assay Kit
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 30011, 30012, 30010, 30019
• Storage Stability: One year from date of receipt when stored as directed.
• Scientific Category: Protein Phosphatase
• Instructions for Use: See assay protocol for detailed instructions.