Tagtociclib (hydrate)

DESCRIPTION

PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).

DETAILS

Purity: >98%
Smiles: O=C(C1=CC(COC)=NN1C)NC2=NNC([C@](CC3)([H])C[C@@H]3OC(NC(C)C)=O)=C2.[H]O[H]
Category: Reference compound
Lead Time: 1-2 days
Cas Number: 2733575-91-0
Molecular Weight: 422.48
Molecular Formula: C19H30N6O5

Lead Time: 1-2 days