T16328
Nitroaspirin
TargetMol
DESCRIPTION
Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin induces significant induction of cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins. Nitroaspirin has antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1.
DETAILS
- Cas: 175033-36-0
- Purity: 98.45%
- Smiles: O(C(C)=O)C1=C(C(OC2=CC(CON(=O)=O)=CC=C2)=O)C=CC=C1
- Category: Compound
- Molecular Weight: 331.28
- Molecular Formula: C16H13NO7
Lead Time: 4 - 5 weeks
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