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36-1585

Monoclonal Antibody to Prolactin Receptor (hPRL-Receptor)(Clone : PRLR742)

Abeomics

DESCRIPTION

It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

DETAILS

  • Gene: PRLR
  • App Id: IHC
  • Antigen: Prolactin Receptor (hPRL-Receptor)
  • Gene Id: 5618
  • Isotype: Mouse IgG1, kappa
  • Format Id: Purified
  • Clone Name: PRLR742
  • Uniprot Id: P16471
  • Host Animal: Mouse
  • Clonality Id: Monoclonal
  • Purification: Affinity Chromatography
  • Reactivity Id: Human
  • Product Content: 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
  • Alternative Name: PRLR
  • Application Note: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes);
  • Storage Condition: Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
  • Immunogen Information: Recombinant human prolactin receptor