mouse monoclonal IgG1; Odin Antibody (F-9) is an IgG1 κ mouse monoclonal Odin antibody (also designated Odin antibody) that detects the Odin protein of mouse, rat and human origin by WB, IP, IF and ELISA. Odin Antibody (F-9) is available as both the non-conjugated anti-Odin antibody form, as well as multiple conjugated forms of anti-Odin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The deduced 1,134-amino acid Odin (ANKS1A) protein plays a putatuve negative role in growth factor receptor signaling pathways. Odin undergoes phosphorylation on tyrosine residues in response to growth factors EGF and PDGF, but not in response to cytokines, such as IL3 or erythropoietin. The PTB domain of Odin is not required for its tyrosine phosphorylation. Odin is a cytoplasmic protein before and after growth factor treatment, and is widely expressed at the protein level. Odin contains six ANK repeats, one PID domain, and two SAM (sterile alpha motif) domains. Overexpression of Odin inhibits EGF-induced activation of the FOS promoter. The gene which encodes Odin, ANKS1A, localizes to chromosome 6p21.31.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.