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E0155Hu

Human Intelectin-1, ITLN1 ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed: 11313366, PubMed: 26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed: 26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris (PubMed: 26148048). Does not bind human glycans (PubMed: 26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed: 16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed: 16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed: 11747454, PubMed: 23921499).

DETAILS

  • GeneID: 55600
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 34,962
  • Synonyms: Endothelial lectin HL-1;Galactofuranose-binding lectin;Intelectin-1;Intestinal lactoferrin receptor;ITLN 1;ITLN1;ITLN-1;Omentin
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: ITLN1
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 1.03ng/L
  • Target Protein: ITLN1
  • Detection Range: 2-600ng/L
  • Full Product Name: Intelectin-1
  • Standard Solution: 640ng/L
  • UniProt Accession: Q8WWA0