Biotinylated Human IL-31 RA Protein, His,Avitag™

DESCRIPTION

Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.

DETAILS

Tag: C-10×His & C-Avi
Host: HEK293
Size: 25ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Biotinylated Human IL-31 RA, His,Avitag (ILA-H82E9) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 519 (Accession # Q8NI17-1).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: IL-31 RA
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ala 20 - Glu 519
Swiss-prot: Q8NI17-1
Package Size: 25ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 60.7 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 60.7 kDa
Shipping Condition: RT
Species Reactivity: Human
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