Mouse SLAMF7 / CRACC / CD319 Protein, Mouse IgG2a Fc Tag, low endotoxin

DESCRIPTION

SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.

DETAILS

Tag: C-mFc(mIgG2a)
Host: HEK293
Size: 100ug
Buffer: 50 mM Tris, 100 mM Glycine, pH7.5
Format: Powder
Purity: 95%
Source: Mouse SLAMF7 Protein, Mouse IgG2a Fc Tag (SL7-M5252) is expressed from human 293 cells (HEK293). It contains AA Ala 22 - Gly 224 (Accession # Q8BHK6-1).
Storage: -20℃
Category: Immune Checkpoint Proteins
Molecule: SLAMF7
Accession: NP_653122.2
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ala 22 - Gly 224
Swiss-prot: Q8BHK6-1
Package Size: 100ug*1
Characteristics: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 49.4 kDa. The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.1 EU per μg
Molecular Weight: 49.4 kDa
Shipping Condition: RT
Species Reactivity: Mouse
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