DESCRIPTION

• Form: Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.
• Host: Rabbit
• Clone: NA
• Label: Unconjugated
• Purity: Affinity purified on immobilized antigen.
• Target: Solute carrier family 41 member 2, Solute carrier family 41 (magnesium transporter), Member 2
• Comment: Contact Alomone Labs for technical support and product customization
• Gene Id: 338365
• Isotype: Rabbit IgG
• Homology: Rat- identical; human - 9/14 amino acid residues identical
• Is Toxin: No
• Sequence: (C)KRSEPHLDYHEFSE, corresponding to amino acid residues 78-91 of mouse SLC41A2
• Synonyms: Solute carrier family 41 member 2, Solute carrier family 41 (magnesium transporter), Member 2
• Accession: Q8BYR8
• Clonality: Polyclonal
• Lead Time: 1-2 Business Days
• Reactivity: Human|Rat|Mouse
• Formulation: PBS pH7.4
• Applications: IFC|IHC|LCI|WB
• Preservative: No Preservative
• Reconstitution: 0.2 ml double distilled water (DDW).
• Blocking Peptide: BLP-NT146
• Negative Control: BLP-NT146
• Positive Control: NA
• Immunogen Location: Extracellular, N-terminus
• Peptide Confirmation: Confirmed by amino acid analysis and mass spectrometry
• Shipping and Storage: Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
• Immunogen Source Species: Mouse
• Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
• Antigen Preadsorption Control: 1 µg peptide per 1 µg antibody
• Applications May Also Work In: IFC|IHC|LCI|WB
• Storage Before Reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
• Product Page - Scientific Background: SLC41A2, Solute carrier family 41 member 2, is a magnesium (Mg2 +) transporter belonging to the SLC41 transporter family, which includes SLC41A1 and SLC41A31.SLC41 proteins appear to possess the same basic structural features of prokaryotic MgtE transporters: they create a Mg2+-selective pore via homodimerization. SLC41 topology suggests the presence of two five TM span domains connected by a TM spanning linker. The N-terminal cytoplasmic domain of SLC41A1 regulates its function2,3.SLC41A2 is highly expressed in lymph nodes, stomach, lungs, testis and skin and is moderately expressed in spleen, intestine, heart, breast and kidneys2.SLC41A2 is reported as either over or under expressed in 75 disease states including a number of carcinomas and lymphomas according to the database on European Bioinformatics Institute (EBI).
• Standard Quality Control of Each Lot: Western blot analysis
• Application Dilutions Western Blot Wb: 1:1000-1:2000
• Antibody Concentration After Reconstitution: 1 mg/ml
• Application Dilutions Immunohistochemistry Paraffin Embedded Sections Ihc: 1:200