31632
IR 780
Cayman Chemical
DESCRIPTION
A fluorescent probe for in vivo tumor cell imaging; ex/em = 780/799 nm; has an additive effect on SDT-induced ROS production increases in 4T1 cells at 16 µM; preferentially accumulates in tumor tissue in MCF-7, HeLa, and MG-63 mouse xenograft models and in a syngeneic mouse model of chemically induced lung tumors; fluorescence is detectable for up to 20 days in vivo; has been incorporated into heparin-folic acid-IR 780 nanoparticles for use in photothermal therapy
DETAILS
- Inchi: InChI=1S/C36H44ClN2.HI/c1-7-24-38-30-18-11-9-16-28(30)35(3,4)32(38)22-20-26-14-13-15-27(34(26)37)21-23-33-36(5,6)29-17-10-12-19-31(29)39(33)25-8-2;/h9-12,16-23H,7-8,13-15,24-25H2,1-6H3;1H/q+1;/p-1
- Purity: ≥98%
- Raptas: Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cancer
- Smiles: ClC1=C(/C=C/C2=[N+](CCC)C3=C(C2(C)C)C=CC=C3)CCC/C1=C\C=C4N(CCC)C5=C(C/4(C)C)C=CC=C5.[I-]
- Inchikey: IRPKBYJYVJOQHQ-UHFFFAOYSA-M
- Cas Number: 207399-07-3
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C36H44ClN2 • I
- Formula Weight: 667.1
- Shelf Life Days: 1460