DESCRIPTION

• Notes: Troubleshooting Guide: Visit bpsbioscience.com/lentivirus-faq for detailed troubleshooting instructions. For all further questions, please email support@bpsbioscience.com
• Uniprot: Q9H422
• Shiptemp: -80°C (dry ice)
• Synonyms: Homeodomain-interacting protein kinase 3, Androgen receptor-interacting nuclear protein kinase, ANPK, Fas-interacting serine/threonine-protein kinase, FIST, Homolog of protein kinase YAK1, HIPK3, DYRK6, FIST3, PKY
• Warnings: Avoid freeze/thaw cycles.
• Category: Kinase/Assay Kit
• Background: HIPK3 (Homeodomain Interacting Protein Kinase 3) is a serine/threonine protein kinase involved in the regulation of gene transcription induced by steroid hormones such as testosterone. Also known as ANPK (Androgen receptor-interacting nuclear protein kinase), it amplifies androgen receptor-mediated transcription. The kinase phosphorylates transcription factors JUN and RNUX2 and may decrease apoptosis through phosphorylation of FADD (FAS-associated death domain protein).
• Description: The HIPK3 Kinase Assay Kit is designed to measure HIPK3 kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. 
• Methodology: Chemiluminescent
• Supplied As: The assay kit comes in a convenient 96-well format, with enough purified recombinant HIPK3 kinase, kinase substrate, ATP, and kinase assay buffer for 100 enzyme reactions.
• Unspsc Code: 41105332
• Unspsc Name: Protein chemiluminescent detection reagents or kits or substrates
• Applications: Study enzyme kinetics and screen small molecular inhibitors for drug discovery and high throughput (HTS) applications.
• Product Type: Assay Kit
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 40179, 40111, 40110, 78487
• Contraindications: The final concentration of DMSO in the assay should not exceed 1%.
• Storage Stability: This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.
• Scientific Category: Kinase