CD3EAP Blocking Peptide (N-term)

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 10849
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: POLR1G
Other Names: DNA-directed RNA polymerase I subunit RPA34, A345, Antisense to ERCC-1 protein, ASE-1, CD3-epsilon-associated protein, CAST, CD3E-associated protein, RNA polymerase I-associated factor PAF49, CD3EAP, ASE1, CAST, PAF49
Availability: 2 weeks
Bio Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. Isoform 2 has been described as a component of preformed T-cell receptor (TCR) complex.
Bio References: Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010) Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009) Vangsted, A.J., et al. Haematologica 94(9):1274-1281(2009) Nissen, K.K., et al. Anticancer Drugs 20(3):174-178(2009) Schierup, M.H., et al. BMC Med. Genet. 10, 20 (2009) :
Other Accession: NP_036231.1
Primary Accession: O15446
Targetspecificity: The synthetic peptide sequence is selected from aa 69-81 of HUMAN CD3EAP