Human Vitronectin / VTN Protein, Tag Free

DESCRIPTION

Vitronectin is also known as S-protein, VN, VTN, V75. Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the formation of the membrane attack complex (MAC), cell adhesion and migration, wound healing, and tissue remodeling. The primary cellular source of vitronectin is hepatocytes. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.

DETAILS

Tag: Native
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Human Vitronectin Protein, Tag Free (VIN-H52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Leu 478 (Accession # P04004).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: Vitronectin
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Asp 20 - Leu 478
Swiss-prot: P04004
Package Size: 200ug*5
Characteristics: This protein carries no "tag". The protein has a calculated MW of 52.3 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.1 EU per μg
Molecular Weight: 52.3 kDa
Shipping Condition: RT
Species Reactivity: Human
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