1014-MSM1-P0 1014-MSM1-P1 1014-MSM1-P1ABX
Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 - CloneID - CDH16/1071
NeoBiotechnologies
DESCRIPTION
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
DETAILS
- Host: Mouse
- Gene ID: 1014
- Uniprot: O75309
- Clone ID: CDH16/1071
- Clonality: Monoclonal
- Gene Name: CDH16
- Supplied As: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Applications: FLOW, IHC, WB
- Protein Target: CDH16
- Species Reactivity: Human, Mouse, Rat, Rabbit, Dog
- Storage Conditions: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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