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sc-365911 SAMPLE sc-365911

Promo Available Scientist.com Supplier

Cacna2d2 (G-5)

Santa Cruz Biotechnology

DESCRIPTION

mouse monoclonal IgG1; Cacna2d2 Antibody (G-5) is an IgG1 κ mouse monoclonal Cacna2d2 antibody (also designated Cacna2d2 antibody) that detects the Cacna2d2 protein of mouse, rat and human origin by WB, IP, IF and ELISA. Cacna2d2 Antibody (G-5) is available as both the non-conjugated anti-Cacna2d2 antibody form, as well as multiple conjugated forms of anti-Cacna2d2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. CACNA2D2 is a gene coding for the protein calcium channel, voltage-dependent alpha2delta-2 (Cacna2d2), a regulatory subunit of the voltage dependent calcium channels. The protein interacts with alpha-1, beta and gamma subunits in a 1:1:1:1 ratio to form a channel mediating calcium influx. Protein expression occurs in the brain, heart, and other tissues, and is involved in central nervous system function. Disruptions of the CACNA2D2 gene may be involved in cerebellar ataxias and epileptic episodes in humans. The gene is localized to the tumor suppressor region of chromosome 3p21.3 in humans. Expression deficiency occurs in lung, breast and other cancers in humans. Part of a family of Alpha2/delta subunits involved in voltage-dependent calcium influx, Cacna2d2 shares 56% amino acid homology with the alpha2/delta-1 subunit, although they have different patterns of tissue expression.

DETAILS

  • Host: mouse
  • Type: Primary
  • Uniprot: Q9NY47
  • Clonality: Monoclonal
  • Conjugate: unconjugated
  • Applications: WB, IP, IF, ELISA
  • Human Gene Id: 9254
  • Mouse Gene Id: 56808
  • Protein Target: Cacna2d2
  • Human Gene Name: CACNA2D2
  • Mouse Gene Name: Cacna2d2
  • Species Reactivity: mouse, rat, human

PROMOTION TERMS

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.