E4830Hu
Human C-C Motif Chemokine 2, CCL2 ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Acts as a ligand for C-C chemokine receptor CCR2 (PubMed: 9837883, PubMed: 10587439, PubMed: 10529171). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed: 9837883, PubMed: 10587439). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed: 8627182, PubMed: 9792674, PubMed: 8195247). May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed: 8107690).
DETAILS
- GeneID: 6347
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 11,025
- Synonyms: C-C motif chemokine 2;CCL 2;CCL2;HC11;MCAF;MCP-1;Monocyte chemoattractant protein 1;Monocyte chemotactic and activating factor;Monocyte chemotactic protein 1;Monocyte secretory protein JE;Small-inducible cytokine A2
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: CCL2
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 3.09ng/L
- Target Protein: CCL2
- Detection Range: 5-1800ng/L
- Full Product Name: C-C Motif Chemokine 2
- Standard Solution: 1920ng/L
- UniProt Accession: P13500