WFDC2 Recombinant Protein

DESCRIPTION

Human Epididymis Protein 4 (HE4) is also known as WAP four-disulfide core domain protein 2 (WFDC2), Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, is a member of the WFDC domain family. HE4 / WFDC2 is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. HE4 is also a small secretory protein, which may be involved in sperm maturation.

DETAILS

Buffer: PBS, pH7.4
Purity: >95% as determined by SDS-PAGE.
Source: HEK293 cells
Species: Human
Storage: Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Shipping: Room Temp
By Source: Human Cells
Swissprot: Q14508
By Species: Human
Fusion Tag: His Tag
Ncbi Gene Id: 10406
Ncbi Organism: homo sapiens
Physical State: Lyophilized
Additional Names: HE4, WAP5, WFDC2, EDDM4
Application Note: This recombinant protein can be used for WB. For research use only.
By Research Area: Apoptosis,Cancer
Protein Accession: AAH46106
Ncbi Official Name: WAP four-disulfide core domain 2
Tested Applications: WB
Ncbi Official Symbol: WFDC2
Background Reference 1: Hellström, Ingegerd, et al., 2003, Cancer Research 63 (13): 3695–3700.
Background Reference 2: Kirchhoff C., et al., 1992, Biol Reprod 45 (2): 350–7.
Background Reference 3: Schummer M., et al., 1999, Gene 238 (2): 375–85.
Predicted Molecular Weight: 10.9 kDa
Recombinant Protein Sequence: Glu 31 - Phe 124