10-10045-25 10-10045
Monoclonal Antibody to SARS-CoV-2 nucleocapsid (Clone: ABM3A11.1B5)
Abeomics
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DESCRIPTION
The structural nucleocapsid (N) protein of nCoV/SARS-CoV-2/COVID-19 is a predicted 46 kDa phosphoprotein having 419 amino acid residues. A short Serine rich stretch and a recognized nuclear localization signal are the unique features of the nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19, which seems to have a little homology with the proteins of other members of this large corona virus family. These features also suggest the involvement of nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 in different stages of viral lifecycle. The protein has multifaceted activities including packing of the nCoV/SARS-CoV-2/COVID-19 viral genome into a helical ribonucleocapsid (RNP) and playing an important role in viral self-assembly causing nCoV/SARS-CoV-2/COVID-19. The nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 also forms dimer in the cell by self-association with the help of interactive C terminal domain.
DETAILS
- Gene: N
- App Id: WB
- Antigen: Nucleocapsid
- Gene Id: 43740575
- Isotype: Mouse IgG1, Kappa
- Format Id: Purified
- Clone Name: ABM3A11.1B5
- Uniprot Id: P0DTC9
- Host Animal: Mouse
- Clonality Id: Monoclonal
- Purification: Protein G Chromatography
- Product Content: 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
- Application Note: Recommended dilutions: WB: 0.1-1 µg/ml. However, this need to be optimized based on the research applications.
- Storage Condition: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
- Immunogen Information: Full length recombinant SARS-CoV-2 nucleocapsid Protein was used as the immunogen for this antibody.