30-2303
PE Conjugated Anti-STRO-1 Monoclonal Antibody (Clone:STRO-1)
Abeomics
DESCRIPTION
STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10% of mononuclear cells, greater than 95% of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells.
DETAILS
- App Id: FACS
- Antigen: STRO-1
- Isotype: Mouse IgM
- Clone Name: STRO-1
- Host Animal: Mouse
- Clonality Id: Monoclonal
- Conjugate Id: PE
- Reactivity Id: Human
- Storage Condition: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
- Immunogen Information: Human CD34 positive bone marrow cells