PSMA5 Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 5686
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: PSMA5
Other Names: Proteasome subunit alpha type-5, Macropain zeta chain, Multicatalytic endopeptidase complex zeta chain, Proteasome zeta chain, PSMA5
Availability: 2 weeks
Bio Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PMA5 is a member of the peptidase T1A family, that is a 20S core alpha subunit.
Primary Accession: P28066
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP1449c was selected from the Center region of human PSMA5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.