Homocarbonyltopsentin

DESCRIPTION

Homocarbonyltopsentin is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing (EC50: 16 μM).

DETAILS

Cas: 172286-77-0
Purity: 98%
Smiles: Oc1ccc2c(c[nH]c2c1)C(=O)c1ncc([nH]1)C(=O)c1c[nH]c2ccccc12
Category: Compound
Molecular Weight: 370.36
Molecular Formula: C21H14N4O3

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