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T13723

Homocarbonyltopsentin

TargetMol

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DETAILS

  • Cas: 172286-77-0
  • Purity: 98%
  • Smiles: C(=O)(C=1C=2C(NC1)=CC(O)=CC2)C=3NC(C(=O)C=4C=5C(NC4)=CC=CC5)=CN3
  • Category: Compound
  • Molecular Weight: 370.36
  • Molecular Formula: C21H14N4O3

DESCRIPTION

Homocarbonyltopsentin is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing (EC50: 16 μM).

Lead Time: 4 - 5 weeks

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