Homocarbonyltopsentin

DESCRIPTION

Homocarbonyltopsentin is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing (EC50: 16 μM).

DETAILS

Cas: 172286-77-0
Purity: 98%
Smiles: C(=O)(C=1C=2C(NC1)=CC(O)=CC2)C=3NC(C(=O)C=4C=5C(NC4)=CC=CC5)=CN3
Category: Compound
Molecular Weight: 370.36
Molecular Formula: C21H14N4O3

Lead Time: 4 - 5 weeks