DESCRIPTION

• Target: LRP4
• Gene Id: 83469
• Isotype: IgG2A
• Conjugate: ATTO 594
• Immunogen: Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4
• References: 1. Bennett V., Baines A.J. (2001) Physiol. Rev. 81 (3): 1353–92.
• Swiss-prot: Q8VI56
• Specificity: Detects the extracellular domain of LRP4 ~215kDa. Degradation product can be seen at ~150kDa.
• Applications: WB | ICC/IF
• Clone Number: N207/27 (Formerly sold as S207-27)
• Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• Host Species: Mouse
• Product Type: Monoclonal
• Purification: Protein G Purified
• Concentration: 1 mg/ml
• Research Areas: Neuroscience | Cell Markers | Neuron Markers | Membrane Markers | Cell Signaling
• Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Accession Number: NP_766256.3
• Alternative Names: Corin Antibody, KIAA0816 Antibody, LDLR Antibody, LDLR dan Antibody, Low density lipoprotein receptor related protein 4 Antibody, LRP-4 Antibody, LRP10 Antibody, MEGF7 Antibody, Multiple epidermal growth factor like domains 7 Antibody
• Antibody Dilution: WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
• Cite This Product: StressMarq Biosciences Cat# SMC-418D-A594, RRID: AB_2701275
• Immunogen Species: Mouse
• Storage Temperature: Conjugated antibodies should be stored according to the product label
• Shipping Temperature: Blue Ice or 4ºC
• Cellular Localization: Membrane
• Scientific Background: Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.
• Certificate of Analysis: 1 µg/ml of SMC-418 was sufficient for detection of LRP4 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Species Reactivity Full Name: Human | Mouse | Rat