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GIR-H82F7-25ug GIR-H82F7-200ug

Biotinylated Human GITR / TNFRSF18 Protein, Fc,Avitag™

ACROBiosystems

DESCRIPTION

Biotinylated Human GITR, Fc,Avitag (GIR-H82F7) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # Q9Y5U5-1).

DETAILS

  • Tag: C-Fc & C-Avi
  • Host: HEK293
  • Size: 25ug
  • Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
  • Format: Powder
  • Purity: 95%
  • Storage: -20℃
  • Category: MABSol® Biotin Labeled Proteins
  • Molecule: GITR
  • Accession: NP_004186.1
  • Conjugate: Biotin-labeled
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
  • Exp Region: Gln 26 - Glu 161
  • Swiss-prot: Q9Y5U5-1
  • Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 43.3 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 43.3 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html