mouse monoclonal IgG1; CNOT11 Antibody (C-6) is an IgG1 κ mouse monoclonal CNOT11 antibody that detects the CNOT11 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. CNOT11 Antibody (C-6) is available as both the non-conjugated anti-CNOT11 antibody form, as well as multiple conjugated forms of anti-CNOT11 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription as well as mRNA degradation. Various subunits within the complex are involved in influencing nuclear hormone receptor activities. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome. CNOT11 (CCR4-NOT transcription complex, subunit 11), also known as C40, is a 510 amino acid protein that belongs to the CNOT11 family. CNOT10 and CNOT11 form a subcomplex docked to the CNOT1 scaffold. CNOT11 is encoded by a gene that maps to human chromosome 2q11.2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.