Ac-IETD-pNA

DESCRIPTION

A caspase-8 substrate; cleavage of the IETD peptide sequence releases p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity

DETAILS

Inchi: InChI=1S/C27H38N6O12/c1-5-13(2)22(28-15(4)35)26(42)30-18(10-11-20(36)37)24(40)32-23(14(3)34)27(43)31-19(12-21(38)39)25(41)29-16-6-8-17(9-7-16)33(44)45/h6-9,13-14,18-19,22-23,34H,5,10-12H2,1-4H3,(H,28,35)(H,29,41)(H,30,42)(H,31,43)(H,32,40)(H,36,37)(H,38,39)/t13-,14+,18-,19-,22-,23-/m0/s1
Purity: ≥95%
Raptas: Application|Enzyme Activity||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases
Smiles: O=C([C@@H](NC([C@H]([C@H](CC)C)NC(C)=O)=O)CCC(O)=O)N[C@H](C(N[C@H](C(NC1=CC=C(C=C1)[N+]([O-])=O)=O)CC(O)=O)=O)[C@@H](C)O
Inchikey: FHURKTIGZAIQGR-BQCLNCLCSA-N
Cas Number: 219138-21-3
Formulation: A lyophilized powder
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C27H38N6O12
Formula Weight: 638.6
Shelf Life Days: 1460