mouse monoclonal IgG2a; E6BP Antibody (30) is an IgG2a κ mouse monoclonal E6BP antibody (also designated E6BP antibody) that detects the E6BP protein of mouse, rat and human origin by WB, IP and IF. E6BP Antibody (30) is available as both the non-conjugated anti-E6BP antibody form, as well as multiple conjugated forms of anti-E6BP antibody, including agarose, HRP. E6BP (reticulocalbin 2, EF-hand calcium binding domain), also known as Rcn2, reticulocalbin-2, TCBP-49, taipoxin-associated calcium-binding protein 49, Erc55 or calcium-binding protein ERC-55, is a 320 amino acid protein with a high affinity for calcium that belongs to the CREC family. Encoded by a gene that maps to human chromosome 15q23, E6BP binds calcium ions and the presynaptic snake venom toxin taipoxin and may interact with internalized taipoxin, possibly mediating its activation. E6BP is expressed in rat brain, cerebellum, heart, liver, kidney, skeletal muscle and testis cells. Although E6BP is homologous to other known S100 proteins and EF-hand proteins, such as calmodulin and calbindin, homolgy is limited to the EF-hand domain. E6BP is also homologous to an identified mouse ER (endoplasmic reticulum) calcium binding protein, reticulocalbin, where homology is not restricted to the EF-hand domain. E6BP is not an abundant protein, which suggests that it is not a reticular calcium storage protein. E6BP is believed to share a general E6-binding motif with E6-AP, which binds cancer-related papillomaviral E6 proteins.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.