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E1563Hu

Human Bone Morphogenetic Protein Receptor 2, BMPR2 ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

DETAILS

  • Gene Id: 659
  • Uniprot: Q13873
  • Lead Time: 3 days
  • Assay Type: Sandwich
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 1.64ng/L
  • Detection Range: 3-900ng/L
  • Detection Method: ELISA
  • Species Reactivity: Human