E1563Hu
Human Bone Morphogenetic Protein Receptor 2, BMPR2 ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
DETAILS
- Gene Id: 659
- Uniprot: Q13873
- Lead Time: 3 days
- Assay Type: Sandwich
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 1.64ng/L
- Detection Range: 3-900ng/L
- Detection Method: ELISA
- Species Reactivity: Human