36-3243-20 36-3243
Anti-CD71 / Transferrin Receptor (TFRC) (Extracellular Domain) Monoclonal Antibody(Clone: TFRC/2898R)
Abeomics
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DESCRIPTION
It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
DETAILS
- App Id: IHC
- Gene Id: 7037
- Isotype: Rabbit IgG
- Clone Name: TFRC/2898R
- Uniprot Id: P02786
- Host Animal: Rabbit
- Clonality Id: Monoclonal
- Reactivity Id: Human
- Product Content: 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Alternative Name: Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR
- Application Note: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);
- Storage Condition: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
- Immunogen Information: Recombinant human extracellular TFRC protein fragment (aa94-212) (exact sequence is proprietary)