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Human Caspase 3, CASP3 ELISA Kit

Bioassay Technology Laboratory


Involved in the activation cascade of caspases responsible for apoptosis execution (PubMed: 7596430). At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond (PubMed: 7774019). Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9 (PubMed: 7596430). Involved in the cleavage of huntingtin (PubMed: 8696339). Triggers cell adhesion in sympathetic neurons through RET cleavage (PubMed: 21357690). Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress (PubMed: 23152800).


  • GeneID: 836
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 31,608
  • Synonyms: Apopain;CASP 3;CASP3;CASP-3;Caspase-3;Caspase-3 subunit p12;Caspase-3 subunit p17;CPP-32;Cysteine protease CPP32;Protein Yama;SCA-1;SREBP cleavage activity 1
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: CASP3
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.027ng/ml
  • Target Protein: CASP3
  • Detection Range: 0.05-20ng/ml
  • Full Product Name: Caspase 3
  • Standard Solution: 24ng/ml
  • UniProt Accession: P42574