GRO-α/KC/CXCL1, Mouse(CHO-expressed)

DESCRIPTION

GRO-α/KC/CXCL1 coded by CXCL1 gene at chromosome 5 is approximately 63% identity to that of mouse MIP2. KC is also approximately 60% identical to the human GROs. Mouse KC is a potent neutrophil attractant and activator. The functional receptor for KC has been identified as CXCR2. Based on the pattern of KC expression in a number of inflammatory disease models, KC appears to have an important role in inflammation. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer’s disease.

DETAILS

Form: Lyophilized
Purity: > 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC
Species: Mouse
Product Line: Chemokines
Expression System: CHO
Storage Stability: Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
Biological Activity: Active at 10.0 ng/ml, measured in a tube formation assay using HUVEC cells.
Protein Construction: GRO-α (Ala25-Lys96)\nAccession # P12850