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11-8014-25 11-8014

Polyclonal Antibody to Exportin-4

Abeomics

DESCRIPTION

Exportin-4 or XPO4 belongs to a large family of nucleoproteins that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments. Exportin-4 is a RanGTP-binding protein and functions as a receptor for nuclear export of EIF-5A and also may have a role as an adapter in RNA export. Exportin-4 has been reported to be involved in nuclear export of Smad3 and thereby regulation of Smad signaling. Diseases associated with XPO4 include pinguecula. This protein has ubiquitously expressed.

DETAILS

  • Gene: XPO4
  • App Id: WB
  • Antigen: Exportin-4
  • Gene Id: 64328
  • Isotype: Rabbit IgG
  • Format Id: Purified
  • Uniprot Id: Q9C0E2
  • Host Animal: Rabbit
  • Clonality Id: Polyclonal
  • Purification: Protein A Chromatography
  • Reactivity Id: Human
  • Product Content: 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
  • Alternative Name: XPO4||KIAA1721
  • Application Note: Western blot analysis: 1-3 µg/ml
  • Storage Condition: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Immunogen Information: A partial length recombinant Exportin-4 protein (amino acids 775-1,000) was used as the immunogen for this antibody.