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Y27632 (10mM in DMSO)

iXCells Biotechnologies


Y27632, 2mg-domestic: 10mM in 624.4ul DMSO-international: shipped as powder; Y27632 is a cell-permeable small molecule Rho-associated kinase (ROCK) inhibitor [1]. Y27632 has been found to prevent apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency [2]. This molecule has also been shown to enhance survival during the transplantation of ES cell-derived neural precursors [3]. Y27632 in combination with Pifithrin-µ significantly improves cell recovery after cryopreservation [4].