DESCRIPTION

• Target: TRPV3
• Gene Id: 497948
• Isotype: IgG2a
• Conjugate: PerCP
• Immunogen: Synthetic peptide amino acids 774-791 (C-terminus) of rat TrpV3
• References: 1. Masamoto Y., Kawabata F., Fushiki T. (2009) Biosci. Biotechnol. Biochem. 73(5): 1021-1027. 2. Xiao R., et al. (2008) J Biol Chem. 283(10): 6162-6174.
• Swiss-prot: Q4QYD9
• Specificity: Detects ~70kDa.
• Applications: WB | IHC | ICC/IF | IP | AM
• Clone Number: N15/4 (Formerly sold as S15-4)
• Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• Host Species: Mouse
• Product Type: Monoclonal
• Purification: Protein G Purified
• Concentration: 1 mg/ml
• Research Areas: Neuroscience | Ion Channels | Transient Receptor Potential (TRP) Channels
• Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Accession Number: NP_001020928
• Alternative Names: 1110036I10Rik Antibody, MGC124324 Antibody, MGC124325 Antibody, Transient receptor potential cation channel subfamily V member 3 Antibody, TrpV3 Antibody, Trpv3 heat sensitive channel Antibody, TRPV3_HUMAN Antibody, Vanilloid receptor 3 Antibody, Vanilloid receptor like 3 Antibody, Vanilloid receptor-like 3 Antibody, vanilloid receptor-related osmotically activated channel protein Antibody, VRL 3,VRL-3 Antibody, VRL3 Antibody
• Antibody Dilution: WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
• Cite This Product: StressMarq Biosciences Cat# SMC-319D-PCP, RRID: AB_2700343
• Immunogen Species: Rat
• Storage Temperature: Conjugated antibodies should be stored according to the product label
• Shipping Temperature: Blue Ice or 4ºC
• Cellular Localization: Membrane
• Scientific Background: The TRPV3 protein belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels (1, 2).
• Certificate of Analysis: 1 µg/ml of SMC-319 was sufficient for detection of TrpV3 in 10 µg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Species Reactivity Full Name: Human | Mouse | Rat