GCNT2 Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 2651
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: GCNT2
Other Names: N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1
Availability: 2 weeks
Bio Background: This gene encodes the enzyme responsible for formation ofthe blood group I antigen. The i and I antigens are distinguishedby linear and branched poly-N-acetyllactosaminoglycans,respectively. The encoded protein is the I-branching enzyme, abeta-1,6-N-acetylglucosaminyltransferase responsible for theconversion of fetal i antigen to adult I antigen in erythrocytesduring embryonic development. Mutations in this gene have beenassociated with adult i blood group phenotype. Alternativelyspliced transcript variants encoding different isoforms have beendescribed.
Bio References: Twu, Y.C., et al. Blood 110(13):4526-4534(2007)Wang, L., et al. Biochem. Biophys. Res. Commun. 331(4):958-963(2005)Pras, E., et al. Invest. Ophthalmol. Vis. Sci. 45(6):1940-1945(2004)Inaba, N., et al. Blood 101(7):2870-2876(2003)Yu, L.C., et al. Blood 101(6):2081-2088(2003)
Primary Accession: Q8N0V5