DESCRIPTION

• Category: REAGENTS
• Keywords: flow cytometry antibody, flow cytometry antibodies, facs antibody, primary antibody, monoclonal antibody, anti-human antibody, Anti human, anti human antibody anti-CD4, CD4, anti CD4, OKT4, Clone OKT4, unconjugated antibody, unconjugated flow cytometry antibody, CD4 antibody, T4, Immunoglobulin, CD Marker, CD Markers, CD Antigen
• Paragraph 1: CD4 is a 55kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is a specific marker for T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. The OKT4 binds to the D3 domain of CD4 and does not inhibit HIV binding
• Paragraph 2: Each lot of these antibodies has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 0.5µg (unconjugated, Biotin) or 5µl (conjugated) of these products are sufficient for staining 1 million cells in a 100µl staining volume or 100µl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance. Non-human primate cross-reactivity has been validated using Caprico’s PerCP-Cyanine5.5 conjugated OKT4 product. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at support@geneseesci.com.
• Bullet Point 1: CD4 is a 55kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily
• Bullet Point 2: Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
• Bullet Point 3: >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
• Bullet Point 4: More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.
• Bullet Point 5: CD4 is also known as T4
• Manufacturer Sku: 100403