71107
PD-L2 (CD273), Fc fusion (Human) HiP™ Recombinant
BPS Bioscience
DESCRIPTION
Human secreted Programmed Death Ligand 2 (PD-L2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, fused at the C-terminus to the Fc portion of human IgG1 expressed in a HEK293 cell expression system. MW = 49 kDa.
DETAILS
- Aa: 20-219
- Mw: 49 kDa
- Tags: C-terminal Fc fusion (Human IgG1)
- Notes: This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. The aggregation state of this product has been confirmed to be <10%.
- Format: Aqueous buffer solution
- Genbank: NM_025238
- Species: Human
- Uniprot: Q9BQ51
- Shiptemp: -80°C (dry ice)
- Synonyms: Programmed Cell Death 2 Ligand 2, PDL2, PD-L2, CD273, PDCDL1G2, B7-DC
- Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
- Category: Immunotherapy/Protein
- References: 1. Latchman, Y., et al., Nat. Immunol. 2001 Mar;2(3):261-8.2. Saunders, P.A., et al., Eur. J. Immunol. 2005 Dec;35(12):3561-9.
- Description: Human secreted Programmed Death Ligand 2 (PD-L2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, fused at the C-terminus to the Fc portion of human IgG1 expressed in a HEK293 cell expression system. MW = 49 kDa.
- Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
- Unspsc Code: 12352202
- Unspsc Name: Proteins
- Applications: Useful for the study of protein-protein interaction and in vitro and in vivo protein function.
- Product Type: Protein
- Biosafety Level: Not applicable (BSL-1)
- Assay Conditions: PD-1-PD-L2 binding activity, measured using the using the PD-1[Biotinylated]:PDL2 Inhibitor Screening Assay Kit, #72006
- Related Products: 71108, 72004, 72005, 72006, 71120
- Storage Stability: At least 6 months at -80°C.
- Scientific Category: Immunotherapy