DESCRIPTION

• Aa: 20-219
• Mw: 49 kDa
• Tags: C-terminal Fc fusion (Human IgG1)
• Notes: This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. The aggregation state of this product has been confirmed to be <10%.
• Format: Aqueous buffer solution
• Genbank: NM_025238
• Species: Human
• Uniprot: Q9BQ51
• Shiptemp: -80°C (dry ice)
• Synonyms: Programmed Cell Death 2 Ligand 2, PDL2, PD-L2, CD273, PDCDL1G2, B7-DC
• Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
• Category: Immunotherapy/Protein
• References: 1. Latchman, Y., et al., Nat. Immunol. 2001 Mar;2(3):261-8.2. Saunders, P.A., et al., Eur. J. Immunol. 2005 Dec;35(12):3561-9.
• Description: Human secreted Programmed Death Ligand 2 (PD-L2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, fused at the C-terminus to the Fc portion of human IgG1 expressed in a HEK293 cell expression system. MW = 49 kDa.
• Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for the study of protein-protein interaction and in vitro and in vivo protein function.
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Assay Conditions: PD-1-PD-L2 binding activity, measured using the using the PD-1[Biotinylated]:PDL2 Inhibitor Screening Assay Kit, #72006
• Related Products: 71108, 72004, 72005, 72006, 71120
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Immunotherapy