Recombinant Murine IL-2

DESCRIPTION

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Murine IL-2 is a 17.2 kDa protein containing 148 amino acid residues.

DETAILS

Gene Id: 16183
Uniprot: P04351
Activity: The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10^6 units/mg.
Category: RUO Cytokines
Subcategory: Growth Factors & Cytokines
Research Areas: AIDS/HIV, Cancer, Cell Culture, Diabetes/Weight Regulation, Immune System, Inflammation, Neurobiology, Stem Cells and Differentiation, Wound Healing, Allergy, Transplantation, CAR T Cell, COVID-19
Alternative Names: T-cell growth factor (TCGF), Aldesleukin
Species of Origin: Murine
Expression System Source: E.coli