T77743
TT-012
TargetMol
DESCRIPTION
TT-012 has anti-tumor activity, selectively binds dynamic MITF and disrupts the dimer formation and DNA binding of the latter. TT-012 can inhibit the transcription of MITF in B16F10 melanoma cells. TT-012 inhibited the growth and metastasis of MITF melanoma cells in animal models. TT-012 is less cytotoxic to liver and immune cells.
DETAILS
- Cas: 1164471-33-3
- Purity: 99.91%
- Smiles: N(C(/C=C/C1=CC=CO1)=O)C=2N=C(NC(/C=C/C3=CC=CO3)=O)C=CC2
- Category: Compound
- Molecular Weight: 349.34
- Molecular Formula: C19H15N3O4
Lead Time: < 1 week
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