Polyclonal Antibody to ASK1 (Ab-83)

DESCRIPTION

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

DETAILS

Gene: MAP3K5
App Id: WB,IHC,IF
Antigen: ASK1 (Ab-83)
Gene Id: 4217
Isotype: Rabbit IgG
Format Id: Purified
Uniprot Id: Q99683
Host Animal: Rabbit
Clonality Id: Polyclonal
Reactivity Id: Human
Product Content: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Alternative Name: ASK-1|| M3K5|| MAP3K5|| MAPK/ERK kinase kinase 5|| MAPKKK5
Application Note: Predicted MW: 155kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Storage Condition: Store the antibody at 4°C, stable for 6 months. For ong-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Immunogen Information: Peptide sequence around aa.81~85 (G-S-S-V-G) derived from Human ASK1.