Panaxatriol

DESCRIPTION

A sapogenin with diverse biological activities; inhibits the proliferation of human DU15 prostate cancer cells (IC50 = 30 μM) and induces apoptosis by increasing production of ROS and decreasing mitochondrial membrane potential; reduces ischemia and reperfusion-induced myocardial dysfunction, increases LVDevP and GSH levels, and decreases cardiac LDH, CK, and MDA levels in isolated rats at 5 mg/kg for seven consecutive days prior to injury; decreases fasting blood glucose levels in KKAy insulin-resistant mice at 0.2% in chow for 6 weeks

DETAILS

Inchi: InChI=1S/C30H52O4/c1-25(2)12-9-13-30(8,34-25)18-10-15-28(6)23(18)19(31)16-21-27(5)14-11-22(33)26(3,4)24(27)20(32)17-29(21,28)7/h18-24,31-33H,9-17H2,1-8H3/t18-,19+,20+,21+,22-,23-,24-,27+,28+,29+,30+/m0/s1
Purity: ≥95%
Raptas: Product Type|Biochemicals|Natural Products|Saponins||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Tumor Microenvironment||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes
Smiles: CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])[C@H](O)C[C@]3(C)[C@]2([H])C[C@@H](O)[C@@]4([H])[C@@]3(C)CC[C@]4([H])[C@]5(C)OC(C)(C)CCC5
Inchikey: QFJUYMMIBFBOJY-UXZRXANASA-N
Cas Number: 32791-84-7
Formulation: A solid
Item Origin: Plant/Panax ginseng
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C30H52O4
Formula Weight: 476.7
Shelf Life Days: 1460