mouse monoclonal IgM; Gα gust Antibody (B-3) is an IgM κ mouse monoclonal Gα gust antibody that detects Gα gust of mouse, rat and human origin by WB, IP, IF and ELISA. Gα gust Antibody (B-3) is available as the non-conjugated anti-Gα gust antibody form, as well as multiple conjugated forms of anti-Gα gust antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Gα subunits have been identified; these include Gs, Gi, Gq and Gα 12/13. Gustducin has been identified as a taste-cell-specific G protein within the Gi subclass of Gα subunit proteins that is most closely related to the transducins and exclusively expressed in taste buds.