GPC3 - CHO-K1 Recombinant Cell Line

DESCRIPTION

Recombinant CHO-K1 cells expressing GPC3 (Glypican 3), a cell surface proteoglycan bearing heparin-sulfate; ref. seq. NM_004484.2.

DETAILS

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Species: Human
Shiptemp: -80°C (dry ice)
Synonyms: Glypican-3 cell line, OCI5 recombinant cell line
Warnings: Avoid freeze/thaw cycles.
Category: Cell Signaling/Cell Line
Background: GPC3, also known as Glypican-3 and OCI5, belongs to the glypican family and is highly expressed in the lungs, liver and kidneys. Its function is tissue dependent and can either promote or suppress tumorigenesis. Being a heparin sulfate proteoglycan, it is overexpressed in neoplasms including malignant melanoma, hepatocellular carcinoma, and testicular yolk sac tumors and plays a significant role in cell growth and differentiation.
Description: Recombinant CHO-K1 cells expressing GPC3 (Glypican 3), a cell surface proteoglycan bearing heparin-sulfate; ref. seq. NM_004484.2.
Supplied As: Each vial contains ~ 2 x 10^6 cells in 1 ml of 10% DMSO in FBS.
Unspsc Code: 41106514
Unspsc Name: Stable mammalian cell lines
Applications: 1. Useful for screening and validating antibodies against GPC3 and anti-GPC3 CAR-T for immunotherapy research and drug discovery.2. Useful for GPC3 binding assays to screen for GPC3 ligands.
Host Species: hamster
Product Type: Cell Line
Host Cell Line: CHO-K1
Biosafety Level: BSL-1
Related Products: 100071, 100072, 60186, 79974
Storage Stability: Cells will arrive upon dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.
Mycoplasma Testing: The cell line has been screened using the MycoAlert™ Mycoplasma Detection kit (Lonza, #LT07-218) to confirm the absence of Mycoplasma species.
Scientific Category: Cell Signaling Pathway
Required Accessories: 60186,79974,79796
Signed License Required: Yes