DESCRIPTION

• Mw: 159 kDa
• Tag: Myc-DDK
• Accn: NM_001128151
• Type: Mouse Tagged ORF Clone
• Refseq: NM_001128151.2
• Status: In Stock*
• Symbol: Cecr2
• Vector: pCMV6-Entry
• Category: cDNA Clones
• Locus Id: 330409
• Orf Size: 4275 bp
• Synonyms: 2610101O16Rik; 2810409N01Rik; Gtl4; mKIAA1740
• Refseq Orf: 4278 bp
• Uniprot Id: E9Q2Z1
• Refseq Size: 9213 bp
• Availability: In Stock
• Cytogenetics: 6 56.97 cM
• Gene Summary: Chromatin reader component of histone-modifying complexes, such as the CERF (CECR2-containing-remodeling factor) complex and ISWI-type complex (By similarity). It thereby plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development (PubMed:15640247, PubMed:20589882, PubMed:21246654). In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes (PubMed:22154806). In histone-modifying complexes, CECR2 recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (By similarity). May also be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis (By similarity).[UniProtKB/Swiss-Prot Function]
• Chromatograms: CHROMATOGRAMS Sequencher program is needed, download here.
• Sequence Data: ORF Nucleotide Sequence ( show hide ) >MR226595 representing NM_001128151 Red =Cloning site Blue=ORF Green =Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGC C ATGTGCCCGGAGGAAGGCGGCGCGGCCGGGCTGGGCGAGCTCCGCTCCTGGTGGGAAGTCCCGGCCATCG CGCACTTCTGCTCGCTCTTTCGCACGGCGTTCCGCCTGCCCGACTTCGAGATCGAGGAGTTAGAGGCAGC TCTTCACAGAGATGACGTGGAGTTTATCAGTGATCTGATTGCCTGCTTGCTTCAAGGCTGCTATCAGCGA AGAGATATCACGCCTCAGACATTCCACAGCTACTTGGAAGATATCATTAACTACCGTTGGGAGCTTGAAG AAGGAAAGCCCAATCCTCTGAGAGAAGCTAGTTTCCAAGACCTTCCTCTGCGTACTCGAGTAGAGATCCT GCATCGCCTCTGTGATTACCGGCTTGATGCAGATGATGTCTTTGATCTTCTCAAGGGTCTGGATGCAGAC AGTCTCAGAGTTGAACCTCTGGGTGAAGACAATTCAGGTGCACTCTACTGGTACTTCTATGGGACACGAA TGTACAAAGAAGACCCAGTACAAGGAAGGTCCAATGGAGAACTCTCCTTGTGCAGGGAAAGTGAAAGGCA AAAAAATGTCTCAAATGTTCCTGGAAAAACAGGCAAAAGAAGAGGAAGGCCTCCAAAGCGAAAAAAGCTA CAGGAGGAGATTATATCCAGTGAAAAGCAGGAAGAAAACTCCTTGACATCTGACCTACAGACAAGAAATG GATCCCGAGGGCCAGGCCAAGGTACTTGGTGGCTCCTGTGTCAAACAGAAGAAGAATGGAGACAGGTCAC TGAGAGCTTCCGAGAGCGGACCTCTCTCCGAGAGCGGCAACTCTACAAGCTCCTTAGCGAGGACTTCCTG CCTGAAATTTGCAACATGATTGCCCAGAAGGGAAAACGTCCACAGCGCACAAAGCCAGAGTTGCAACATA GGTTTATGTCTGACCACCTGTCCATCAAATCCATCAAGCTAGAGGAAACTCCCATGCTCACCAAGATAGA AAAACAGAAGCGCAGGGAGGAGGAGGAGGAGCGACAGCTCCTTCTTGCCGTGCAGAAGAAGGAGCAAGAG CAGATGTTAAAGGAGGAGAGAAAGCGGGAAATGGAGGAAAAGGTCAAGGCAGTGGAAGATCGAGCTAAGA GGAGAAAGCTCAGGGAAGAACGAGCATGGCTATTGGCTCAAGGCAAGGAGCTACCCCCAGAACTTTCCCA TTTGGACCTGAATTCTCCTATGAGGGAAGGGAAGAAGACCAAGGACCTCTTTGAATTGGATGACGATTTC ACAGCCATGTATAAAGTTCTAGATGTGGTGAAGGCTCACAAGGATTCCTGGCCCTTCTTGGAACCTGTGG ATGAATCGTATGCCCCCAACTATTACCAGATTATTAAGATCCCCATGGATATTTCAAGCATGGAGAAGAA ATTAAACGGAGGTTTATATTGTAACAAGGAGGAATTTGTAAATGACATGAAGACCATGTTCAGAAATTGC CGAAAATACAATGGTGACAGTAGTGAGTATACCAAGATGTCTGACAATTTAGAGCGGTGTTTCCATCGGG CCATGACAAAACATTTTCCTGGTGAAGATGGAGACACAGATGAAGAATTTTGGATCAAAGAGGATGAAAA ACGGGAAAAAAGAAGAAGTCGGTCTGGTAGAAGTAGTGGAAGCCATGTTTGGACGCGCTCCAGAGACACA GAAGGGTCGAGCAGGAAACAGCCACCAGTGGAGAATGGGGGAAAATCATTGCCCCCGGCACGCCGAGCTG CCTCCTCAGGGGACGATCAGAGTAGGAGTTCCATACAACTCCCTCCAGAGAGGCCAGCAGCACCAGGAAC ATTTGGCTCTCTTCAAGGATCAGATCCCACCAACTTACATGGCTCCTCTAGAATCCCAGAGGCTCCCCCA GGAGAGCCCTTGCAACACCCACCCTTTGCTATACAGGCTCCAGTTGGAATTAGTAACCATCGGGGATCCC TGCTCAGTGCTCCAGACCTTTCCAATATGGGGTCACATGTCCCATCCTTACAGCTTGGGCAGATGAATTG TCCCAGTCAAGATGGAAACATGTATCCACCAGCTCCATTCCAGGCAGGATTTATTCCTTCTAGGCATGGT GGGACTCCAGCCCGACCCCCAGACTTTCCTGAAAGCTCTGAAATTCCTCCCGGTCATATTTATCATTCAT ACAAGTATCTAAATCGAGCACACCCTGCTGTTTGGAATGGGAACCATGGTACTACAAACCCTGGACGTTT GGGGCCAGATGAGAAGCCCCACCTGGGGCCAGGACCCTCTCACCACCCTCATACCCTTGGTCATATGATG GATGGCCGAGTGATGAGACAACCTATCCCACCAAACCAGTGGACTAAACAGTCAAGCTTTCTACCTCATG GAGTTCCTTCCTCGGGGTATATGCAGCCACCCTGTAAGTCTGCTGGACATCGTTTGCAGCCACCTCCAAC TCCAGCACCAAGTCCTCGATTCAGAGGGCCCTCCCAGGCCCTCCGGGGGGCACAAGGAGGGGAATCCATG ATGGACAGCCCTGAAATGATTGCCATGCAGCAGCTCTCCTCCCGAGTCTGTCCCCCAGGTGTGCCTTACC ACCCCCGCCAGCCCACTCCTCCCCAGTTACCTGGTCCCTTTCCGCAGGTAGCTCATTCAGCTTCAGTCTG TGTGTCGGCGCCCAAGCCTGCATTGGACAACCCTGGGAGTACACAGGAGATGACTGAAACACACGAGCCC GAGGAAGACCCAGCAGAGCCTTTGCCTGGACATGAAGAGAAAGCAGCAAGCATTTGTTCTTCAGAGGGGG TATACCTCAAACAGCTACCTCACCCAGCACCTCCCTTGCAAGCCAGCTGTACCAGGCAAAGCTCACCACA AGAAAGGGAAACAGAGGACTCCCAACTCAAAAGTGATGCTTCAGACTCTGCAGACACTTATAAGACATCA AAGAACAAGAACACCTGGCCTTTGGACAATAGCTACAGCAGCCCAGCTGTGCAAGGCTGTTTGAGGGACC TCTCCATAGTGGCAGAGACGGGGAATCTACCTGAAAATGGGGTCGTTGGTGAAGCATCTCCCTGTAGGTC AGAGGGGAAGGGCCTTGATGGTAGTGGTTCAGAAAAGCCACTCTGCCCCAGGGGTAAAACATTGCAAGAA GCCGTGCCATGTACAGGACCGAATGCAACTACACCTCCTTGCACAGATCCCAGTTTGATGGCAGCCACTG TGAACCAGTTTTCTCCCTTATACATGCCTGGCATAGAATACTCTAACTCAGCTACACAGTACCCTATGAG TCCAAGTTTGCAAGGTTTGGCCTCTATGATGGGAGGAAAGTCCTCAGGATCACAACCTCAGTCCTTTCCT CCCAGGGGTTTCCAGGCTAATGGTCCCCACCCTGGACTCTTTCCTCGGTACCGTCCTCAGCAGGGAATGA GATATTCCTACCAGCCGCCTTCTCAGCCTTCCTACCACCCCTATCAGCGGACTCCTTATTATACATGTCC ACAGGGCTTTTCTGATTGGCAGAGATCTCTCCCTTCCCAGAGAAGCCCAAGTGGACCCCCAGGAAGTCAC CCTCCACGCTCCCTCTTTTCAGAGAAGAATGTCCTGTCTAGTCTGCAAGGTTGTGAAACATTAAATACTG CCTTAACTTCTCCAACTCAAATGGATGTAGTGACTGCTAAAGTTGTTCCTCCTGATGGACACAATTCTGG TCCAGAAGAAGAAAAGATGGATGAATCTGTGGAGAGGCCAGAGAGTCCCAAAGAATTTCTAGATCTCGAC AACCATAATGCAGCTACCAAGCGGCAGAACTCACTGTCAACCAGTGACTATCTTTATGGAACTCCACCAC CATCTCTGAGTTCAGGAATGACTTTTGGTTCATCTGCTTTCCCACCCCACAGTGTGATGCTGCAGACAGG GTCTCCATACACTCCTCAGCGATCAGCCAGTCATTTTCAGCCCAGGGCATACCCATCCCCTGTGCCTGCC CATCCACCTCCCCATCCAGTAGCCACCCAACCCAATGGCCTCTCTCCAGAGGATTCCCTCTACTGCTGTC AGGAAGAGGGCCTAGGTCACTTTCAGGCTTCGATGATGGAGCAGACTGGTACCGGAAGCGGATTAAGAGG CTCATTTCAAGAAGTACACAGACCACCAGGATTGCAGATGCATCCAGTGCAGTCACAGTCCTTATTCCCA AAGACCCCGGCACCTGCAGCATCACCAGAACAGTTGCCACCGCATAAGACCCCAACGCTTCCTCTGGATC AGAGC ACGCGT ACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAG GTTTAA Protein Sequence ( show hide ) >MR226595 representing NM_001128151 Red =Cloning site Green =Tags(s) MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQR RDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRLCDYRLDADDVFDLLKGLDAD SLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGRSNGELSLCRESERQKNVSNVPGKTGKRRGRPPKRKKL QEEIISSEKQEENSLTSDLQTRNGSRGPGQGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFL PEICNMIAQKGKRPQRTKPELQHRFMSDHLSIKSIKLEETPMLTKIEKQKRREEEEERQLLLAVQKKEQE QMLKEERKREMEEKVKAVEDRAKRRKLREERAWLLAQGKELPPELSHLDLNSPMREGKKTKDLFELDDDF TAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKIPMDISSMEKKLNGGLYCNKEEFVNDMKTMFRNC RKYNGDSSEYTKMSDNLERCFHRAMTKHFPGEDGDTDEEFWIKEDEKREKRRSRSGRSSGSHVWTRSRDT EGSSRKQPPVENGGKSLPPARRAASSGDDQSRSSIQLPPERPAAPGTFGSLQGSDPTNLHGSSRIPEAPP GEPLQHPPFAIQAPVGISNHRGSLLSAPDLSNMGSHVPSLQLGQMNCPSQDGNMYPPAPFQAGFIPSRHG GTPARPPDFPESSEIPPGHIYHSYKYLNRAHPAVWNGNHGTTNPGRLGPDEKPHLGPGPSHHPHTLGHMM DGRVMRQPIPPNQWTKQSSFLPHGVPSSGYMQPPCKSAGHRLQPPPTPAPSPRFRGPSQALRGAQGGESM MDSPEMIAMQQLSSRVCPPGVPYHPRQPTPPQLPGPFPQVAHSASVCVSAPKPALDNPGSTQEMTETHEP EEDPAEPLPGHEEKAASICSSEGVYLKQLPHPAPPLQASCTRQSSPQERETEDSQLKSDASDSADTYKTS KNKNTWPLDNSYSSPAVQGCLRDLSIVAETGNLPENGVVGEASPCRSEGKGLDGSGSEKPLCPRGKTLQE AVPCTGPNATTPPCTDPSLMAATVNQFSPLYMPGIEYSNSATQYPMSPSLQGLASMMGGKSSGSQPQSFP PRGFQANGPHPGLFPRYRPQQGMRYSYQPPSQPSYHPYQRTPYYTCPQGFSDWQRSLPSQRSPSGPPGSH PPRSLFSEKNVLSSLQGCETLNTALTSPTQMDVVTAKVVPPDGHNSGPEEEKMDESVERPESPKEFLDLD NHNAATKRQNSLSTSDYLYGTPPPSLSSGMTFGSSAFPPHSVMLQTGSPYTPQRSASHFQPRAYPSPVPA HPPPHPVATQPNGLSPEDSLYCCQEEGLGHFQASMMEQTGTGSGLRGSFQEVHRPPGLQMHPVQSQSLFP KTPAPAASPEQLPPHKTPTLPLDQS TR TRPLEQKLISEEDLAANDILDYKDDDDK V
• Oti Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Oti Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Reconstitution: 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• E Coli Selection: Kanamycin (25 ug/mL)
• Restriction Sites: SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Mammalian Cell Selection: Neomycin