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Z03313-1

Scientist.com Supplier

CNTF, Rat

GenScript

DESCRIPTION

Ciliary Neurotrophic Factor (CNTF) is a polypeptide hormone which acts within the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. CNTF is a potent survival factor for neurons and oligodendrocytes and may play a role in reducing tissue damage during increased inflammation. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, however this phenotype is not causally related to neurologic disease.

DETAILS

  • Form: Lyophilized
  • Purity: > 95% as analyzed by SDS-PAGE
  • Species: Rat
  • Product Line: Growth Factors
  • Expression System: E. coli
  • Storage Stability: Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
  • Biological Activity: ED50 < 30.0 ng/ml, measured by its ability to induce alkaline phosphatase production by TF-1 Cells.
  • Protein Construction: CNTF (Ala2-Met200)\nAccession # P20294-1