Skip to Main Content
More Intelligent Procurement, Faster R&D

Go to Main Navigation

ET7110-28

Scientist.com Supplier

Anti-KIFAP3 Antibody [JE52-70]

HuaBio

DESCRIPTION

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.

DETAILS

  • Host: Rabbit
  • Type: Primary
  • Uniprot: SwissProt: Q92845 Human;SwissProt: P70188 Mouse;SwissProt: D3ZWA5 Rat
  • Clone Id: JE52-70
  • Clonality: Recombinant Rabbit monoclonal Antibody
  • Conjugate: Non-conjugated
  • Alias Names: FLJ22818 antibody KAP 3 antibody KAP-3 antibody KAP3 antibody KIF3AP antibody KIFA3_HUMAN antibody Kifap3 antibody Kinesin associated protein 3 antibody Kinesin-associated protein 3 antibody SMAP antibody Smg GDS antibody Smg GDS associated protein antibody Smg GDS-associated protein antibody
  • Application: WB,IF-Cell,IHC-P,FC
  • Epitope Region: Recombinant protein within Human KIFAP3 aa 635-792 / 792.
  • Protein Target: KIFAP3
  • Target Species: Human,Mouse,Rat
  • Species Reactivity: Human,Mouse,Rat