ET7110-28
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Anti-KIFAP3 Antibody [JE52-70]
HuaBio
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DESCRIPTION
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.
DETAILS
- Host: Rabbit
- Type: Primary
- Uniprot: SwissProt: Q92845 Human;SwissProt: P70188 Mouse;SwissProt: D3ZWA5 Rat
- Clone Id: JE52-70
- Clonality: Recombinant Rabbit monoclonal Antibody
- Conjugate: Non-conjugated
- Alias Names: FLJ22818 antibody KAP 3 antibody KAP-3 antibody KAP3 antibody KIF3AP antibody KIFA3_HUMAN antibody Kifap3 antibody Kinesin associated protein 3 antibody Kinesin-associated protein 3 antibody SMAP antibody Smg GDS antibody Smg GDS associated protein antibody Smg GDS-associated protein antibody
- Application: WB,IF-Cell,IHC-P,FC
- Epitope Region: Recombinant protein within Human KIFAP3 aa 635-792 / 792.
- Protein Target: KIFAP3
- Target Species: Human,Mouse,Rat
- Species Reactivity: Human,Mouse,Rat