Skip to Main Content
Welcome to the Scientist.com Marketplace

Go to Main Navigation

T14304

Aphidicolin

TargetMol

Thumbnail image

DETAILS

  • Cas: 38966-21-1
  • Purity: 98%
  • Smiles: C[C@@]12[C@]34[C@](C[C@](C3)([C@](CO)(O)CC4)[H])(CC[C@]1([C@@](CO)(C)[C@H](O)CC2)[H])[H]
  • Category: Compound
  • Molecular Weight: 338.48
  • Molecular Formula: C20H34O4

DESCRIPTION

Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets DNA polymerase α and δ, disrupting mitotic cell division by affecting DNA polymerase activity[1]. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].

Lead Time: 4 - 5 weeks

Sign in to view pricing