DESCRIPTION

• Shiptemp: -80°C (dry ice)
• Warnings: Avoid freeze/thaw cycles.
• Category: Kinase/Assay Kit
• References: Alicea, N.L. et al., Current Drug Targets 12(4):546-555 (2011)
• Description: Janus kinase (JAK) is a family of intracellular, nonreceptor tyrosine kinases that play an important role in cytokine-mediated signaling. This family includes four protein kinases; Jak1, Jak2, Jak3 and Tyk2. Various studies have suggested that regulation of Jak activity should be a promising approach to combat numerous diseases such as immune deficiencies and cancers. The JAK2 (Janus Kinase 2) Assay Kit is designed to measure JAK2 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The JAK2 (Janus Kinase 2) Assay Kit comes in a convenient 96-well format, with enough purified recombinant JAK2 enzyme, JAK2 substrate peptide (Poly(Glu;Tyr, 4:1)), ATP and kinase assay buffer for 100 enzyme reactions.
• Methodology: Chemiluminescent
• Unspsc Code: 41105332
• Unspsc Name: Protein chemiluminescent detection reagents or kits or substrates
• Applications: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
• Product Type: Assay Kit
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 40452, 40449, 79521, 79518, 78487
• Storage Stability: Up to 6 months when stored as recommended.
• Scientific Category: Kinase
• Instructions for Use: See assay kit datasheet for detailed protocol.