T74088
Fludarabine triphosphate trisodium
TargetMol
DESCRIPTION
Fludarabine triphosphate (F-ara-ATP) trisodium, the principal metabolite of Fludarabine, acts as a potent, noncompetitive, and specific inhibitor of DNA primase, exhibiting an IC50 value of 2.3 μM and a Ki of 6.1 μM. It hampers DNA synthesis by obstructing DNA primase and the formation of primer RNA, while also inhibiting ribonucleotide reductase and DNA polymerase activities, effectively inducing cellular apoptosis [1] [2].
DETAILS
- Purity: 98%
- Smiles: #N/A
- Category: Compound
- Molecular Weight: 591.12
- Molecular Formula: C10H12FN5Na3O13P3
Lead Time: 4 - 5 weeks
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