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sc-514672

Scientist.com Supplier

Morc3 (G-12)

Santa Cruz Biotechnology

DESCRIPTION:
mouse monoclonal IgG1; Morc3 Antibody (G-12) is an IgG1 κ mouse monoclonal Morc3 antibody (also designated Morc3 antibody) that detects the Morc3 protein of mouse, rat and human origin by WB, IP, IF and ELISA. Morc3 Antibody (G-12) is available as both the non-conjugated anti-Morc3 antibody form, as well as multiple conjugated forms of anti-Morc3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The Microrchidia (Morc) family of proteins includes four predicted members in human (Morc1, Morc2, Morc3 and Morc4) and five in mice (Morc1, Morc2a, Morc2b, Morc3 and Morc4). MORC family CW-type zinc finger protein 3 (Morc3), also known as zinc finger CW-type coiled-coil domain protein 3 (ZCWCC3), is a 939 amino acid protein belonging to the MORC family. Ubiquitously expressed in human cell lines, Morc3 contains one CW-type zinc finger and is localized to the nuclear matrix. Morc3 has been shown to play a role in recruiting p53 and SP-100 to promyelocytic leukemia (PML)-nuclear bodies (NBs). Furthermore, Morc3 regulates p53 activation in a manner dependent on Morc3-ATPase activity.

DETAILS

  • Host: mouse
  • Uniprot: Q14149
  • Clonality: Monoclonal
  • Conjugate: unconjugated
  • Applications: WB, IP, IF, ELISA
  • Human Gene Id: 23515
  • Mouse Gene Id: 338467
  • Protein Target: Morc3
  • Human Gene Name: MORC3
  • Mouse Gene Name: Morc3
  • Species Reactivity: mouse, rat, human